BDBM50160699 CHEMBL3786460

SMILES: CC(C)(C)NC(=O)C1N(Cc2ccccc2-c2ccc(F)c(F)c2)C(=O)c2ccccc12

InChI Key: InChIKey=CEUDRLRJBJINQH-GOSISDBHSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50160699   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel subunit Kv1.5 (Homo sapiens (Human))	BDBM50160699 (CHEMBL3786460) Show SMILES CC(C)(C)NC(=O)C1N(Cc2ccccc2-c2ccc(F)c(F)c2)C(=O)c2ccccc12 Show InChI InChI=1S/C22H33Cl2N7O2S/c1-14(2)18(28-22(25)26)7-10-27-34(32,33)31-11-8-15(9-12-31)20-13-19(29-30(20)3)16-5-4-6-17(23)21(16)24/h4-6,13-15,18,27H,7-12H2,1-3H3,(H4,25,26,28)/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel by QPatch-clamp method				Bioorg Med Chem Lett 26: 2023-9 (2016) BindingDB Entry DOI: 10.7270/Q2D220HH
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50160699 (CHEMBL3786460) Show SMILES CC(C)(C)NC(=O)C1N(Cc2ccccc2-c2ccc(F)c(F)c2)C(=O)c2ccccc12 Show InChI InChI=1S/C22H33Cl2N7O2S/c1-14(2)18(28-22(25)26)7-10-27-34(32,33)31-11-8-15(9-12-31)20-13-19(29-30(20)3)16-5-4-6-17(23)21(16)24/h4-6,13-15,18,27H,7-12H2,1-3H3,(H4,25,26,28)/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human ERG				Bioorg Med Chem Lett 26: 2023-9 (2016) BindingDB Entry DOI: 10.7270/Q2D220HH
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50160699 (CHEMBL3786460) Show SMILES CC(C)(C)NC(=O)C1N(Cc2ccccc2-c2ccc(F)c(F)c2)C(=O)c2ccccc12 Show InChI InChI=1S/C22H33Cl2N7O2S/c1-14(2)18(28-22(25)26)7-10-27-34(32,33)31-11-8-15(9-12-31)20-13-19(29-30(20)3)16-5-4-6-17(23)21(16)24/h4-6,13-15,18,27H,7-12H2,1-3H3,(H4,25,26,28)/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human ERG				Bioorg Med Chem Lett 26: 2023-9 (2016) BindingDB Entry DOI: 10.7270/Q2D220HH
					More data for this Ligand-Target Pair
Voltage-gated potassium channel subunit Kv1.5 (Homo sapiens (Human))	BDBM50160699 (CHEMBL3786460) Show SMILES CC(C)(C)NC(=O)C1N(Cc2ccccc2-c2ccc(F)c(F)c2)C(=O)c2ccccc12 Show InChI InChI=1S/C22H33Cl2N7O2S/c1-14(2)18(28-22(25)26)7-10-27-34(32,33)31-11-8-15(9-12-31)20-13-19(29-30(20)3)16-5-4-6-17(23)21(16)24/h4-6,13-15,18,27H,7-12H2,1-3H3,(H4,25,26,28)/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel by QPatch-clamp method				Bioorg Med Chem Lett 26: 2023-9 (2016) BindingDB Entry DOI: 10.7270/Q2D220HH
					More data for this Ligand-Target Pair