BDBM50160918 CHEMBL182662::N-{3-[3-(2-Benzyloxy-5-chloro-phenyl)-thiophen-2-yl]-phenyl}-C-phenyl-methanesulfonamide
SMILES: Clc1ccc(OCc2ccccc2)c(c1)-c1ccsc1-c1cccc(NS(=O)(=O)Cc2ccccc2)c1
InChI Key: InChIKey=DOFJFNAZXDVIHD-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E2 receptor EP1 subtype (EP1) (Homo sapiens (Human)) | BDBM50160918 (CHEMBL182662 | N-{3-[3-(2-Benzyloxy-5-chloro-pheny...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 52 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Binding affinity against Prostaglandin E receptor was determined in human | Bioorg Med Chem Lett 15: 1155-60 (2005) Article DOI: 10.1016/j.bmcl.2004.12.005 BindingDB Entry DOI: 10.7270/Q2SF2VNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP1 subtype (EP1) (Homo sapiens (Human)) | BDBM50160918 (CHEMBL182662 | N-{3-[3-(2-Benzyloxy-5-chloro-pheny...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 72 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Binding affinity against Prostaglandin E receptor in presence of 2% human serum albumin | Bioorg Med Chem Lett 15: 1155-60 (2005) Article DOI: 10.1016/j.bmcl.2004.12.005 BindingDB Entry DOI: 10.7270/Q2SF2VNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid TP receptor (Homo sapiens (Human)) | BDBM50160918 (CHEMBL182662 | N-{3-[3-(2-Benzyloxy-5-chloro-pheny...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | >2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Binding affinity against human Prostanoid TP receptor | Bioorg Med Chem Lett 15: 1155-60 (2005) Article DOI: 10.1016/j.bmcl.2004.12.005 BindingDB Entry DOI: 10.7270/Q2SF2VNV | |||||||||||
More data for this Ligand-Target Pair |