BDBM50161042 3-(2,6-Dichloro-phenyl)-5-methyl-isoxazole-4-carboxylic acid [2-(azepane-1-carbonyl)-phenyl]-amide::CHEMBL436275

SMILES: Cc1onc(c1C(=O)Nc1ccccc1C(=O)N1CCCCCC1)-c1c(Cl)cccc1Cl

InChI Key: InChIKey=ODLASSFTHORNDH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50161042   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50161042 (3-(2,6-Dichloro-phenyl)-5-methyl-isoxazole-4-carbo...) Show SMILES Cc1onc(c1C(=O)Nc1ccccc1C(=O)N1CCCCCC1)-c1c(Cl)cccc1Cl |(-2.05,1.99,;-3,.78,;-4.53,.86,;-5.07,-.57,;-3.88,-1.52,;-2.6,-.68,;-1.14,-1.08,;-.74,-2.57,;-.05,,;1.44,-.38,;2.21,-1.68,;3.77,-1.68,;4.51,-.33,;3.72,.99,;2.19,.97,;2.19,2.5,;1.09,3.6,;3.26,3.6,;2.74,5.06,;3.56,6.36,;5.09,6.55,;6.19,5.46,;6.02,3.92,;4.72,3.09,;-3.79,-3.05,;-2.44,-3.75,;-.95,-4.16,;-2.35,-5.31,;-3.63,-6.14,;-5,-5.43,;-5.09,-3.91,;-6.47,-3.23,)| Show InChI InChI=1S/C24H23Cl2N3O3/c1-15-20(22(28-32-15)21-17(25)10-8-11-18(21)26)23(30)27-19-12-5-4-9-16(19)24(31)29-13-6-2-3-7-14-29/h4-5,8-12H,2-3,6-7,13-14H2,1H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of binding to human growth hormone secretagogue receptor				Bioorg Med Chem Lett 15: 1201-4 (2005) Article DOI: 10.1016/j.bmcl.2004.11.075 BindingDB Entry DOI: 10.7270/Q24Q7THD
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50161042 (3-(2,6-Dichloro-phenyl)-5-methyl-isoxazole-4-carbo...) Show SMILES Cc1onc(c1C(=O)Nc1ccccc1C(=O)N1CCCCCC1)-c1c(Cl)cccc1Cl |(-2.05,1.99,;-3,.78,;-4.53,.86,;-5.07,-.57,;-3.88,-1.52,;-2.6,-.68,;-1.14,-1.08,;-.74,-2.57,;-.05,,;1.44,-.38,;2.21,-1.68,;3.77,-1.68,;4.51,-.33,;3.72,.99,;2.19,.97,;2.19,2.5,;1.09,3.6,;3.26,3.6,;2.74,5.06,;3.56,6.36,;5.09,6.55,;6.19,5.46,;6.02,3.92,;4.72,3.09,;-3.79,-3.05,;-2.44,-3.75,;-.95,-4.16,;-2.35,-5.31,;-3.63,-6.14,;-5,-5.43,;-5.09,-3.91,;-6.47,-3.23,)| Show InChI InChI=1S/C24H23Cl2N3O3/c1-15-20(22(28-32-15)21-17(25)10-8-11-18(21)26)23(30)27-19-12-5-4-9-16(19)24(31)29-13-6-2-3-7-14-29/h4-5,8-12H,2-3,6-7,13-14H2,1H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of ghrelin-induced increase of intracellular [Ca2+] in CHO¿K cell FLIPR assay				Bioorg Med Chem Lett 15: 1201-4 (2005) Article DOI: 10.1016/j.bmcl.2004.11.075 BindingDB Entry DOI: 10.7270/Q24Q7THD
					More data for this Ligand-Target Pair