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BDBM50161110 CHEMBL3792639

SMILES: Cc1cc(O)ccc1-c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1cccc2n(C)ccc12

InChI Key: InChIKey=BTTHVHBJKLEXKW-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50161110   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear receptor ROR-gamma (RORC)


(Homo sapiens (Human))
BDBM50161110
PNG
(CHEMBL3792639)
Show SMILES Cc1cc(O)ccc1-c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1cccc2n(C)ccc12
Show InChI InChI=1S/C24H21F3N2O3S/c1-16-14-19(30)10-11-20(16)17-6-8-18(9-7-17)29(15-24(25,26)27)33(31,32)23-5-3-4-22-21(23)12-13-28(22)2/h3-14,30H,15H2,1-2H3
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 210n/an/an/an/an/an/a



Biogen

Curated by ChEMBL


Assay Description
Inverse agonist activity at recombinant human GST-tagged ROR-gamma receptor ligand binding domain assessed as inhibition of receptor and co-activator...


Bioorg Med Chem Lett 26: 2459-63 (2016)


BindingDB Entry DOI: 10.7270/Q2QC05DC
More data for this
Ligand-Target Pair