BDBM50161652 CHEMBL3785293

SMILES: O[C@@H]1[C@@H](CNC(=O)CCl)O[C@H]([C@H](O)[C@H]1O)n1cc(Cc2ccc(cc2)C2CC2)c2c(Cl)cccc12

InChI Key: InChIKey=BUJCKZHCUXHUJG-DDLBMNSQSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50161652   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50161652 (CHEMBL3785293) Show SMILES O[C@@H]1[C@@H](CNC(=O)CCl)O[C@H]([C@H](O)[C@H]1O)n1cc(Cc2ccc(cc2)C2CC2)c2c(Cl)cccc12 |r| Show InChI InChI=1S/C26H28Cl2N2O5/c27-11-21(31)29-12-20-23(32)24(33)25(34)26(35-20)30-13-17(22-18(28)2-1-3-19(22)30)10-14-4-6-15(7-5-14)16-8-9-16/h1-7,13,16,20,23-26,32-34H,8-12H2,(H,29,31)/t20-,23-,24+,25-,26-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	113	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting method				Bioorg Med Chem 24: 2242-50 (2016) BindingDB Entry DOI: 10.7270/Q25D8TQP
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (SGLT1) (Homo sapiens (Human))	BDBM50161652 (CHEMBL3785293) Show SMILES O[C@@H]1[C@@H](CNC(=O)CCl)O[C@H]([C@H](O)[C@H]1O)n1cc(Cc2ccc(cc2)C2CC2)c2c(Cl)cccc12 |r| Show InChI InChI=1S/C26H28Cl2N2O5/c27-11-21(31)29-12-20-23(32)24(33)25(34)26(35-20)30-13-17(22-18(28)2-1-3-19(22)30)10-14-4-6-15(7-5-14)16-8-9-16/h1-7,13,16,20,23-26,32-34H,8-12H2,(H,29,31)/t20-,23-,24+,25-,26-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.05E+3	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting method				Bioorg Med Chem 24: 2242-50 (2016) BindingDB Entry DOI: 10.7270/Q25D8TQP
					More data for this Ligand-Target Pair