BDBM50161827 CHEMBL3785762

SMILES: Cc1ccc(Nc2nc(O)nc(Nc3ccc(C)cc3)n2)cc1

InChI Key: InChIKey=POXQZKPYJBJIJC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50161827   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50161827 (CHEMBL3785762) Show SMILES Cc1ccc(Nc2nc(O)nc(Nc3ccc(C)cc3)n2)cc1 Show InChI InChI=1S/C17H17N5O/c1-11-3-7-13(8-4-11)18-15-20-16(22-17(23)21-15)19-14-9-5-12(2)6-10-14/h3-10H,1-2H3,(H3,18,19,20,21,22,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tartu Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase using 234-nt long RNA/18-mer DNA oligonucleotide as template/primer preincubated for 15 mins followed by inc...				Bioorg Med Chem 24: 2519-29 (2016) BindingDB Entry DOI: 10.7270/Q2NC632Q
					More data for this Ligand-Target Pair