BDBM50162356 1-[2-Biphenyl-4-yl-2-(4-cyclohexyl-piperazin-1-yl)-ethyl]-3-(3,5-dimethyl-phenyl)-urea::CHEMBL195214

SMILES: Cc1cc(C)cc(NC(=O)NCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)-c2ccccc2)c1

InChI Key: InChIKey=DDHJYTODSBZYIU-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50162356   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50162356 (1-[2-Biphenyl-4-yl-2-(4-cyclohexyl-piperazin-1-yl)...) Show SMILES Cc1cc(C)cc(NC(=O)NCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)-c2ccccc2)c1 Show InChI InChI=1S/C33H42N4O/c1-25-21-26(2)23-30(22-25)35-33(38)34-24-32(29-15-13-28(14-16-29)27-9-5-3-6-10-27)37-19-17-36(18-20-37)31-11-7-4-8-12-31/h3,5-6,9-10,13-16,21-23,31-32H,4,7-8,11-12,17-20,24H2,1-2H3,(H2,34,35,38)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	326	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biographics Laboratory 3R Curated by ChEMBL					Assay Description Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)				J Med Chem 48: 1515-27 (2005) Article DOI: 10.1021/jm040827u BindingDB Entry DOI: 10.7270/Q2KK9B8W
					More data for this Ligand-Target Pair