BDBM50162498 CHEMBL1578072
SMILES: Cc1c(sc2ncn(C)c(=O)c12)C(O)=O
InChI Key: InChIKey=UXEKRAQXZUUDCB-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Branched-chain-amino-acid aminotransferase, mitochondrial (Homo sapiens (Human)) | BDBM50162498 (CHEMBL1578072) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | 6.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline R&D Curated by ChEMBL | Assay Description Inhibition of human BCATm incubated for 10 mins by Amplex red- based fluorescence analysis | J Med Chem 59: 2452-67 (2016) BindingDB Entry DOI: 10.7270/Q2GQ70NC | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |