BDBM50162785 3-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxymethyl]-N-methyl-benzamide::CHEMBL182438

SMILES: CNC(=O)c1cccc(COc2ccc3cc(ccc3c2)C(C(C)N(C)C)n2ccnc2)c1

InChI Key: InChIKey=YRZCYALYRQWTET-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50162785   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50162785 (3-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naph...) Show SMILES CNC(=O)c1cccc(COc2ccc3cc(ccc3c2)C(C(C)N(C)C)n2ccnc2)c1 Show InChI InChI=1S/C27H30N4O2/c1-19(30(3)4)26(31-13-12-29-18-31)23-9-8-22-16-25(11-10-21(22)15-23)33-17-20-6-5-7-24(14-20)27(32)28-2/h5-16,18-19,26H,17H2,1-4H3,(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	397	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Selectivity towards cytochrome P450 3A4 enzyme activity				Bioorg Med Chem Lett 15: 1669-73 (2005) Article DOI: 10.1016/j.bmcl.2005.01.044 BindingDB Entry DOI: 10.7270/Q2WW7H5R
					More data for this Ligand-Target Pair
Cytochrome CYP26A1 (Homo sapiens (Human))	BDBM50162785 (3-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naph...) Show SMILES CNC(=O)c1cccc(COc2ccc3cc(ccc3c2)C(C(C)N(C)C)n2ccnc2)c1 Show InChI InChI=1S/C27H30N4O2/c1-19(30(3)4)26(31-13-12-29-18-31)23-9-8-22-16-25(11-10-21(22)15-23)33-17-20-6-5-7-24(14-20)27(32)28-2/h5-16,18-19,26H,17H2,1-4H3,(H,28,32)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Potency towards cytochrome P 450 26 enzyme activity				Bioorg Med Chem Lett 15: 1669-73 (2005) Article DOI: 10.1016/j.bmcl.2005.01.044 BindingDB Entry DOI: 10.7270/Q2WW7H5R
					More data for this Ligand-Target Pair