BDBM50163128 2-(2,4-Dichloro-phenyl)-1-(4-fluoro-phenyl)-5-methyl-1H-imidazole-4-carboxylic acid piperidin-1-ylamide::CHEMBL175368
SMILES: Cc1c(nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(F)cc1)C(=O)NN1CCCCC1
InChI Key: InChIKey=PIQKCFMGYGBVIK-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50163128 (2-(2,4-Dichloro-phenyl)-1-(4-fluoro-phenyl)-5-meth...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 52 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro displacement of CP-55940 binding to human CB1 receptor expressed in CHO cells | J Med Chem 48: 1823-38 (2005) Article DOI: 10.1021/jm040843r BindingDB Entry DOI: 10.7270/Q2251JX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50163128 (2-(2,4-Dichloro-phenyl)-1-(4-fluoro-phenyl)-5-meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 765 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro displacement of CP-55940 binding to human CB2 receptor expressed in CHO cells | J Med Chem 48: 1823-38 (2005) Article DOI: 10.1021/jm040843r BindingDB Entry DOI: 10.7270/Q2251JX2 | |||||||||||
More data for this Ligand-Target Pair |