BDBM50163385 CHEMBL3792999

SMILES: Cc1ccc(C(O)=O)c(C)c1NC(=O)c1nc(ccc1C)N1CCC(C)(O)CC1

InChI Key: InChIKey=DMKYRXNSYOVNLS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50163385   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50163385 (CHEMBL3792999) Show SMILES Cc1ccc(C(O)=O)c(C)c1NC(=O)c1nc(ccc1C)N1CCC(C)(O)CC1 Show InChI InChI=1S/C22H27N3O4/c1-13-5-7-16(21(27)28)15(3)18(13)24-20(26)19-14(2)6-8-17(23-19)25-11-9-22(4,29)10-12-25/h5-8,29H,9-12H2,1-4H3,(H,24,26)(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity against human EP4 expressed in HEK293 cells assessed as inhibition of PGE2-stimulated production of cAMP incubated for 20 mins by...				Bioorg Med Chem Lett 26: 2303-7 (2016) BindingDB Entry DOI: 10.7270/Q22F7QBJ
					More data for this Ligand-Target Pair