BDBM50163998 4-(4-Methoxy-benzenesulfonyl)-4-o-tolyl-piperidine-1-carboxylic acid ethyl ester::CHEMBL360341

SMILES: CCOC(=O)N1CCC(CC1)(c1ccccc1C)S(=O)(=O)c1ccc(OC)cc1

InChI Key: InChIKey=IDPRRKIFQPJKDZ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50163998   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta amyloid A4 protein (Homo sapiens (Human))	BDBM50163998 (4-(4-Methoxy-benzenesulfonyl)-4-o-tolyl-piperidine...) Show SMILES CCOC(=O)N1CCC(CC1)(c1ccccc1C)S(=O)(=O)c1ccc(OC)cc1 Show InChI InChI=1S/C22H27NO5S/c1-4-28-21(24)23-15-13-22(14-16-23,20-8-6-5-7-17(20)2)29(25,26)19-11-9-18(27-3)10-12-19/h5-12H,4,13-16H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.45E+4	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description In vitro effective concentration against beta amyloid protein 40 in ELISA				Bioorg Med Chem Lett 15: 1891-4 (2005) Article DOI: 10.1016/j.bmcl.2005.02.006 BindingDB Entry DOI: 10.7270/Q2N879B4
					More data for this Ligand-Target Pair