BDBM50164118 6-(2-Chloro-6-trifluoromethyl-phenyl)-8-methyl-2-phenylamino-8H-pyrido[2,3-d]pyrimidin-7-one::CHEMBL360698

SMILES: Cn1c2nc(Nc3ccccc3)ncc2cc(-c2c(Cl)cccc2C(F)(F)F)c1=O

InChI Key: InChIKey=ALUWXRODNZKFAY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164118   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Wee1-like protein kinase (Homo sapiens (Human))	BDBM50164118 (6-(2-Chloro-6-trifluoromethyl-phenyl)-8-methyl-2-p...) Show SMILES Cn1c2nc(Nc3ccccc3)ncc2cc(-c2c(Cl)cccc2C(F)(F)F)c1=O |(.75,-3.34,;.75,-1.8,;-.6,-1.03,;-1.93,-1.82,;-3.26,-1.03,;-4.59,-1.82,;-5.93,-1.03,;-7.25,-1.83,;-8.58,-1.07,;-8.59,.48,;-7.25,1.26,;-5.92,.49,;-3.26,.51,;-1.93,1.28,;-.6,.51,;.73,1.28,;2.06,.51,;3.39,1.3,;3.39,2.82,;2.04,3.59,;4.7,3.61,;6.05,2.85,;6.05,1.31,;4.72,.53,;4.74,-1.01,;6.28,-1.01,;3.65,.09,;4.72,-2.55,;2.08,-1.03,;3.41,-1.78,)| Show InChI InChI=1S/C21H14ClF3N4O/c1-29-18-12(11-26-20(28-18)27-13-6-3-2-4-7-13)10-14(19(29)30)17-15(21(23,24)25)8-5-9-16(17)22/h2-11H,1H3,(H,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of checkpoint kinase Wee1				Bioorg Med Chem Lett 15: 1931-5 (2005) Article DOI: 10.1016/j.bmcl.2005.01.079 BindingDB Entry DOI: 10.7270/Q280524M
					More data for this Ligand-Target Pair