BDBM50164223 2-{Imidazo[1,2-d][1,2,4]thiadiazol-3-yl-[6-(2-nitro-benzenesulfonylamino)-hexyl]-amino}-acetamide::CHEMBL440383

SMILES: NC(=O)CN(CCCCCCNS(=O)(=O)c1ccccc1[N+]([O-])=O)c1n[s+]c2[n-]ccn12

InChI Key: InChIKey=PPZNRHXFQCQZMR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50164223   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor XIII (Homo sapiens (Human))	BDBM50164223 (2-{Imidazo[1,2-d][1,2,4]thiadiazol-3-yl-[6-(2-nitr...) Show SMILES NC(=O)CN(CCCCCCNS(=O)(=O)c1ccccc1[N+]([O-])=O)c1n[s+]c2[n-]ccn12 Show InChI InChI=1S/C18H23N7O5S2/c19-16(26)13-23(17-22-31-18-20-10-12-24(17)18)11-6-2-1-5-9-21-32(29,30)15-8-4-3-7-14(15)25(27)28/h3-4,7-8,10,12,21H,1-2,5-6,9,11,13H2,(H2,19,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Apotex Research Inc. Curated by ChEMBL					Assay Description In vitro inhibitory concentration of compound against factor XIIIa				J Med Chem 48: 2266-9 (2005) Article DOI: 10.1021/jm049221w BindingDB Entry DOI: 10.7270/Q2R210XM
					More data for this Ligand-Target Pair
Transglutaminase-1 (TG1) (Homo sapiens (Human))	BDBM50164223 (2-{Imidazo[1,2-d][1,2,4]thiadiazol-3-yl-[6-(2-nitr...) Show SMILES NC(=O)CN(CCCCCCNS(=O)(=O)c1ccccc1[N+]([O-])=O)c1n[s+]c2[n-]ccn12 Show InChI InChI=1S/C18H23N7O5S2/c19-16(26)13-23(17-22-31-18-20-10-12-24(17)18)11-6-2-1-5-9-21-32(29,30)15-8-4-3-7-14(15)25(27)28/h3-4,7-8,10,12,21H,1-2,5-6,9,11,13H2,(H2,19,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Apotex Research Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against guinea pig liver transglutaminase				J Med Chem 48: 2266-9 (2005) Article DOI: 10.1021/jm049221w BindingDB Entry DOI: 10.7270/Q2R210XM
					More data for this Ligand-Target Pair