BDBM50165113 CHEMBL3797671

SMILES: Cc1ccc(cc1)N(CC(=O)Nc1ccc(cc1)C#N)S(=O)(=O)Cc1ccc(F)cc1

InChI Key: InChIKey=ZIOFMOWAXVRBME-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50165113   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM50165113 (CHEMBL3797671) Show SMILES Cc1ccc(cc1)N(CC(=O)Nc1ccc(cc1)C#N)S(=O)(=O)Cc1ccc(F)cc1 Show InChI InChI=1S/C23H20FN3O3S/c1-17-2-12-22(13-3-17)27(31(29,30)16-19-4-8-20(24)9-5-19)15-23(28)26-21-10-6-18(14-25)7-11-21/h2-13H,15-16H2,1H3,(H,26,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jilin University Curated by ChEMBL					Assay Description Inhibition of Gal4-RORgamma-LBD (180 to 507 residues) (unknown origin) expressed in HEK293T cells after 24 hrs by dual-luciferase reporter assay				Eur J Med Chem 116: 13-26 (2016) BindingDB Entry DOI: 10.7270/Q2TT4SVK
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM50165113 (CHEMBL3797671) Show SMILES Cc1ccc(cc1)N(CC(=O)Nc1ccc(cc1)C#N)S(=O)(=O)Cc1ccc(F)cc1 Show InChI InChI=1S/C23H20FN3O3S/c1-17-2-12-22(13-3-17)27(31(29,30)16-19-4-8-20(24)9-5-19)15-23(28)26-21-10-6-18(14-25)7-11-21/h2-13H,15-16H2,1H3,(H,26,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
Jilin University Curated by ChEMBL					Assay Description Displacement of N-terminal biotinylated SRC1-4 coactivator peptide from N-terminal His6-fused human RORgamma-LBD (262 to 507 residues) expressed in E...				Eur J Med Chem 116: 13-26 (2016) BindingDB Entry DOI: 10.7270/Q2TT4SVK
					More data for this Ligand-Target Pair