BDBM50165564 CHEMBL3798590

SMILES: CC(C)(C)OC(=O)N1CCC(CC1)n1cc(cn1)-c1cnc2nnc(Cc3ccc4ncccc4c3)n2n1

InChI Key: InChIKey=YNGFALOUSKCJJX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50165564   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50165564 (CHEMBL3798590) Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)n1cc(cn1)-c1cnc2nnc(Cc3ccc4ncccc4c3)n2n1 Show InChI InChI=1S/C27H29N9O2/c1-27(2,3)38-26(37)34-11-8-21(9-12-34)35-17-20(15-30-35)23-16-29-25-32-31-24(36(25)33-23)14-18-6-7-22-19(13-18)5-4-10-28-22/h4-7,10,13,15-17,21H,8-9,11-12,14H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISA				Eur J Med Chem 116: 239-251 (2016) BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair