BDBM50166578 CHEMBL3799153

SMILES: CC(C)n1ncc2ccc(cc12)C(=O)Nc1nnc(s1)C1CC1

InChI Key: InChIKey=IJUZUIJUNJWLQQ-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50166578   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50166578 (CHEMBL3799153) Show SMILES CC(C)n1ncc2ccc(cc12)C(=O)Nc1nnc(s1)C1CC1 Show InChI InChI=1S/C16H17N5OS/c1-9(2)21-13-7-11(5-6-12(13)8-17-21)14(22)18-16-20-19-15(23-16)10-3-4-10/h5-10H,3-4H2,1-2H3,(H,18,20,22)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	584	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human recombinant EP3 receptor expressed in human Chem1 cell membrane by scintillation proximity assay				Bioorg Med Chem Lett 26: 2670-5 (2016) Article DOI: 10.1016/j.bmcl.2016.04.009 BindingDB Entry DOI: 10.7270/Q2CJ8GDR
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50166578 (CHEMBL3799153) Show SMILES CC(C)n1ncc2ccc(cc12)C(=O)Nc1nnc(s1)C1CC1 Show InChI InChI=1S/C16H17N5OS/c1-9(2)21-13-7-11(5-6-12(13)8-17-21)14(22)18-16-20-19-15(23-16)10-3-4-10/h5-10H,3-4H2,1-2H3,(H,18,20,22)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant EP3 receptor expressed in CHOK1 cells assessed as inhibition of sulprostone-induced decrease in cAMP level p...				Bioorg Med Chem Lett 26: 2670-5 (2016) Article DOI: 10.1016/j.bmcl.2016.04.009 BindingDB Entry DOI: 10.7270/Q2CJ8GDR
					More data for this Ligand-Target Pair