BDBM50166896 4-Benzyl-3-(4-chloro-phenyl)-7-hydroxy-chromen-2-one::CHEMBL193518

SMILES: Oc1ccc2c(Cc3ccccc3)c(-c3ccc(Cl)cc3)c(=O)oc2c1

InChI Key: InChIKey=DNLRVCHWGNMSCA-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50166896   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estradiol receptor beta (ERβ) (Homo sapiens (Human))	BDBM50166896 (4-Benzyl-3-(4-chloro-phenyl)-7-hydroxy-chromen-2-o...) Show SMILES Oc1ccc2c(Cc3ccccc3)c(-c3ccc(Cl)cc3)c(=O)oc2c1 Show InChI InChI=1S/C22H15ClO3/c23-16-8-6-15(7-9-16)21-19(12-14-4-2-1-3-5-14)18-11-10-17(24)13-20(18)26-22(21)25/h1-11,13,24H,12H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Binding affinity for human Estrogen receptor beta				J Med Chem 48: 3463-6 (2005) Article DOI: 10.1021/jm0490538 BindingDB Entry DOI: 10.7270/Q2WS8V00
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50166896 (4-Benzyl-3-(4-chloro-phenyl)-7-hydroxy-chromen-2-o...) Show SMILES Oc1ccc2c(Cc3ccccc3)c(-c3ccc(Cl)cc3)c(=O)oc2c1 Show InChI InChI=1S/C22H15ClO3/c23-16-8-6-15(7-9-16)21-19(12-14-4-2-1-3-5-14)18-11-10-17(24)13-20(18)26-22(21)25/h1-11,13,24H,12H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Binding affinity for human Estrogen receptor Alpha				J Med Chem 48: 3463-6 (2005) Article DOI: 10.1021/jm0490538 BindingDB Entry DOI: 10.7270/Q2WS8V00
					More data for this Ligand-Target Pair
Estradiol receptor beta (ERβ) (Homo sapiens (Human))	BDBM50166896 (4-Benzyl-3-(4-chloro-phenyl)-7-hydroxy-chromen-2-o...) Show SMILES Oc1ccc2c(Cc3ccccc3)c(-c3ccc(Cl)cc3)c(=O)oc2c1 Show InChI InChI=1S/C22H15ClO3/c23-16-8-6-15(7-9-16)21-19(12-14-4-2-1-3-5-14)18-11-10-17(24)13-20(18)26-22(21)25/h1-11,13,24H,12H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Binding affinity for human Estrogen receptor beta				J Med Chem 48: 3463-6 (2005) Article DOI: 10.1021/jm0490538 BindingDB Entry DOI: 10.7270/Q2WS8V00
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50166896 (4-Benzyl-3-(4-chloro-phenyl)-7-hydroxy-chromen-2-o...) Show SMILES Oc1ccc2c(Cc3ccccc3)c(-c3ccc(Cl)cc3)c(=O)oc2c1 Show InChI InChI=1S/C22H15ClO3/c23-16-8-6-15(7-9-16)21-19(12-14-4-2-1-3-5-14)18-11-10-17(24)13-20(18)26-22(21)25/h1-11,13,24H,12H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Binding affinity for human Estrogen receptor Alpha				J Med Chem 48: 3463-6 (2005) Article DOI: 10.1021/jm0490538 BindingDB Entry DOI: 10.7270/Q2WS8V00
					More data for this Ligand-Target Pair