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SMILES: Nc1cnc(-c2ccc(O)c(Cl)c2)c(n1)-c1ccccc1

InChI Key: InChIKey=CFYKVIYFEZGVRI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 501675   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Adenosine receptor A2a


(Homo sapiens (Human))		BDBM501675
PNG
(US11028058, Compound 1.1)
Show SMILES Nc1cnc(-c2ccc(O)c(Cl)c2)c(n1)-c1ccccc1
Show InChI InChI=1S/C16H12ClN3O/c17-12-8-11(6-7-13(12)21)15-16(20-14(18)9-19-15)10-4-2-1-3-5-10/h1-9,21H,(H2,18,20)
PDB
MMDB

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KEGG

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PC cid
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US Patent
n/an/a 57n/an/an/an/an/an/a



NUVATION BIO INC.

US Patent


Assay Description
For the A2A adenosine receptor radioligand binding assay, the following modifications were made to the general protocol. GF/C filters (Perkin Elmer, ...

US Patent US11028058 (2021)


BindingDB Entry DOI: 10.7270/Q23J3H46
More data for this
Ligand-Target Pair