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BDBM50167683 (2S,4S)-4-Benzyl-1-[(S)-5-guanidino-2-(2-naphthalen-2-yl-acetylamino)-pentanoyl]-pyrrolidine-2-carboxylic acid benzylamide::CHEMBL439522

SMILES: NC(=N)NCCC[C@H](NC(=O)Cc1ccc2ccccc2c1)C(=O)N1C[C@@H](Cc2ccccc2)C[C@H]1C(=O)NCc1ccccc1

InChI Key: InChIKey=DZEMZHXEKMDTDY-LENAEUCASA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50167683   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocyte-stimulating hormone receptor


(Homo sapiens (Human))
BDBM50167683
PNG
((2S,4S)-4-Benzyl-1-[(S)-5-guanidino-2-(2-naphthale...)
Show SMILES NC(=N)NCCC[C@H](NC(=O)Cc1ccc2ccccc2c1)C(=O)N1C[C@@H](Cc2ccccc2)C[C@H]1C(=O)NCc1ccccc1
Show InChI InChI=1S/C37H42N6O3/c38-37(39)40-19-9-16-32(42-34(44)23-28-17-18-30-14-7-8-15-31(30)21-28)36(46)43-25-29(20-26-10-3-1-4-11-26)22-33(43)35(45)41-24-27-12-5-2-6-13-27/h1-8,10-15,17-18,21,29,32-33H,9,16,19-20,22-25H2,(H,41,45)(H,42,44)(H4,38,39,40)/t29-,32-,33-/m0/s1
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>5.00E+3n/an/an/an/an/an/an/an/a



Procter& Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity towards human Melanocortin 1 Receptor


Bioorg Med Chem Lett 15: 2819-23 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.120
BindingDB Entry DOI: 10.7270/Q2F76DBS
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50167683
PNG
((2S,4S)-4-Benzyl-1-[(S)-5-guanidino-2-(2-naphthale...)
Show SMILES NC(=N)NCCC[C@H](NC(=O)Cc1ccc2ccccc2c1)C(=O)N1C[C@@H](Cc2ccccc2)C[C@H]1C(=O)NCc1ccccc1
Show InChI InChI=1S/C37H42N6O3/c38-37(39)40-19-9-16-32(42-34(44)23-28-17-18-30-14-7-8-15-31(30)21-28)36(46)43-25-29(20-26-10-3-1-4-11-26)22-33(43)35(45)41-24-27-12-5-2-6-13-27/h1-8,10-15,17-18,21,29,32-33H,9,16,19-20,22-25H2,(H,41,45)(H,42,44)(H4,38,39,40)/t29-,32-,33-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>5.00E+4n/an/an/an/an/an/an/an/a



Procter& Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity towards human Melanocortin 4 Receptor


Bioorg Med Chem Lett 15: 2819-23 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.120
BindingDB Entry DOI: 10.7270/Q2F76DBS
More data for this
Ligand-Target Pair