BDBM50167726 (R)-5-Acetimidoylamino-2-(S)-amino-3-methyl-pentanoic acid::CHEMBL370170
SMILES: C[C@H](CCNC(C)=N)[C@H](N)C(O)=O
InChI Key: InChIKey=XEDNXCBJUXAGJM-VDTYLAMSSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nitric oxide synthase, inducible (Homo sapiens (Human)) | BDBM50167726![]() ((R)-5-Acetimidoylamino-2-(S)-amino-3-methyl-pentan...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Nagoya City University Curated by ChEMBL | Assay Description Inhibitory concentration against human inducible nitric oxide synthase expressed in Sf-9 cells | Bioorg Med Chem Lett 15: 2881-5 (2005) Article DOI: 10.1016/j.bmcl.2005.03.078 BindingDB Entry DOI: 10.7270/Q2PK0FP1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, brain (Homo sapiens (Human)) | BDBM50167726![]() ((R)-5-Acetimidoylamino-2-(S)-amino-3-methyl-pentan...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Nagoya City University Curated by ChEMBL | Assay Description Inhibitory concentration against human neuronal nitric oxide synthase expressed in Sf-9 cells | Bioorg Med Chem Lett 15: 2881-5 (2005) Article DOI: 10.1016/j.bmcl.2005.03.078 BindingDB Entry DOI: 10.7270/Q2PK0FP1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, endothelial (Homo sapiens (Human)) | BDBM50167726![]() ((R)-5-Acetimidoylamino-2-(S)-amino-3-methyl-pentan...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Nagoya City University Curated by ChEMBL | Assay Description Inhibitory concentration against human endothelial nitric oxide synthase expressed in Sf-9 cells | Bioorg Med Chem Lett 15: 2881-5 (2005) Article DOI: 10.1016/j.bmcl.2005.03.078 BindingDB Entry DOI: 10.7270/Q2PK0FP1 | |||||||||||
More data for this Ligand-Target Pair |