null

SMILES: OC(=O)CCNC(=O)c1ccc2C(CCc2c1)n1nc(cc1-c1ccc(F)cc1)-c1cc(Cl)cc(Cl)c1

InChI Key: InChIKey=HJIJRAAIWKMTEJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50168097   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM50168097 (CHEMBL3798135) Show SMILES OC(=O)CCNC(=O)c1ccc2C(CCc2c1)n1nc(cc1-c1ccc(F)cc1)-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C28H22Cl2FN3O3/c29-20-12-19(13-21(30)14-20)24-15-26(16-1-5-22(31)6-2-16)34(33-24)25-8-4-17-11-18(3-7-23(17)25)28(37)32-10-9-27(35)36/h1-3,5-7,11-15,25H,4,8-10H2,(H,32,37)(H,35,36)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Antagonist activity at wild type human glucagon receptor expressed in HEK293T cells assessed as inhibition of glucagon-induced cAMP accumulation incu...				Bioorg Med Chem 24: 2852-63 (2016) BindingDB Entry DOI: 10.7270/Q27P919J
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50168097 (CHEMBL3798135) Show SMILES OC(=O)CCNC(=O)c1ccc2C(CCc2c1)n1nc(cc1-c1ccc(F)cc1)-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C28H22Cl2FN3O3/c29-20-12-19(13-21(30)14-20)24-15-26(16-1-5-22(31)6-2-16)34(33-24)25-8-4-17-11-18(3-7-23(17)25)28(37)32-10-9-27(35)36/h1-3,5-7,11-15,25H,4,8-10H2,(H,32,37)(H,35,36)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from wild type human glucagon receptor expressed in CHO-K1 cells after 3 hrs by scintillation counting method				Bioorg Med Chem 24: 2852-63 (2016) BindingDB Entry DOI: 10.7270/Q27P919J
					More data for this Ligand-Target Pair