US11028058, Compound 1.315

SMILES: Cn1ccc(n1)-c1nc(N)cnc1-c1ccc2c(cc[nH]c2=O)c1

InChI Key: InChIKey=IDZSPDWWNNMBBJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 501685   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A2a (Homo sapiens (Human))	BDBM501685 (US11028058, Compound 1.315) Show SMILES Cn1ccc(n1)-c1nc(N)cnc1-c1ccc2c(cc[nH]c2=O)c1 Show InChI InChI=1S/C17H14N6O/c1-23-7-5-13(22-23)16-15(20-9-14(18)21-16)11-2-3-12-10(8-11)4-6-19-17(12)24/h2-9H,1H3,(H2,18,21)(H,19,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	101	n/a	n/a	n/a	n/a	n/a	n/a
NUVATION BIO INC. US Patent					Assay Description For the A2A adenosine receptor radioligand binding assay, the following modifications were made to the general protocol. GF/C filters (Perkin Elmer, ...				US Patent US11028058 (2021)
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