BDBM50169590 2-Ethyl-7-(2,4,6-trimethyl-phenyl)-6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-carboxylic acid (4-chloro-benzyl)-(3,3,3-trifluoro-propyl)-amide::CHEMBL181053

SMILES: CCc1nc2N(CCn2c1C(=O)N(CCC(F)(F)F)Cc1ccc(Cl)cc1)c1c(C)cc(C)cc1C

InChI Key: InChIKey=DUMBFQIXBWMFNM-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50169590   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50169590 (2-Ethyl-7-(2,4,6-trimethyl-phenyl)-6,7-dihydro-5H-...) Show SMILES CCc1nc2N(CCn2c1C(=O)N(CCC(F)(F)F)Cc1ccc(Cl)cc1)c1c(C)cc(C)cc1C Show InChI InChI=1S/C27H30ClF3N4O/c1-5-22-24(25(36)33(11-10-27(29,30)31)16-20-6-8-21(28)9-7-20)35-13-12-34(26(35)32-22)23-18(3)14-17(2)15-19(23)4/h6-9,14-15H,5,10-13,16H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]-Tyr-o- CRF from human corticotropin releasing factor receptor 1 expressed in IMR-32 cells				Bioorg Med Chem Lett 15: 3870-3 (2005) Article DOI: 10.1016/j.bmcl.2005.05.117 BindingDB Entry DOI: 10.7270/Q269733T
					More data for this Ligand-Target Pair