BDBM50169667 Acetic acid [4-(thiazol-2-ylcarbamoyl)-thiazol-5-ylcarbamoyl]-methyl ester::CHEMBL179431

SMILES: CC(=O)OCC(=O)Nc1scnc1C(=O)Nc1nccs1

InChI Key: InChIKey=ZJCXKUHRQUYJFH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169667   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 1 (Saccharomyces cerevisiae)	BDBM50169667 (Acetic acid [4-(thiazol-2-ylcarbamoyl)-thiazol-5-y...) Show SMILES CC(=O)OCC(=O)Nc1scnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C11H10N4O4S2/c1-6(16)19-4-7(17)14-10-8(13-5-21-10)9(18)15-11-12-2-3-20-11/h2-3,5H,4H2,1H3,(H,14,17)(H,12,15,18)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration required against Saccharomyces cerevisiae MetAP1 (330 nM)				Bioorg Med Chem Lett 15: 3732-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.055 BindingDB Entry DOI: 10.7270/Q2T1534B
					More data for this Ligand-Target Pair
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50169667 (Acetic acid [4-(thiazol-2-ylcarbamoyl)-thiazol-5-y...) Show SMILES CC(=O)OCC(=O)Nc1scnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C11H10N4O4S2/c1-6(16)19-4-7(17)14-10-8(13-5-21-10)9(18)15-11-12-2-3-20-11/h2-3,5H,4H2,1H3,(H,14,17)(H,12,15,18)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration required against Escherichia coli MetAP1 (150 nM)				Bioorg Med Chem Lett 15: 3732-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.055 BindingDB Entry DOI: 10.7270/Q2T1534B
					More data for this Ligand-Target Pair