BDBM50170211 (R)-Phenyl-{[4-(4-trifluoromethoxy-phenyl)-thiophene-2-carbonyl]-amino}-acetic acid::CHEMBL178652

SMILES: OC(=O)[C@H](NC(=O)c1cc(cs1)-c1ccc(OC(F)(F)F)cc1)c1ccccc1

InChI Key: InChIKey=QSXWMSOERGLVDJ-QGZVFWFLSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50170211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-12 (MMP12) (Homo sapiens (Human))	BDBM50170211 ((R)-Phenyl-{[4-(4-trifluoromethoxy-phenyl)-thiophe...) Show SMILES OC(=O)[C@H](NC(=O)c1cc(cs1)-c1ccc(OC(F)(F)F)cc1)c1ccccc1 Show InChI InChI=1S/C20H14F3NO4S/c21-20(22,23)28-15-8-6-12(7-9-15)14-10-16(29-11-14)18(25)24-17(19(26)27)13-4-2-1-3-5-13/h1-11,17H,(H,24,25)(H,26,27)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Matrix metalloprotease-12 in presence of 5 nM acetohydroximate				Bioorg Med Chem Lett 15: 3787-90 (2005) Article DOI: 10.1016/j.bmcl.2005.05.079 BindingDB Entry DOI: 10.7270/Q2736QFM
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50170211 ((R)-Phenyl-{[4-(4-trifluoromethoxy-phenyl)-thiophe...) Show SMILES OC(=O)[C@H](NC(=O)c1cc(cs1)-c1ccc(OC(F)(F)F)cc1)c1ccccc1 Show InChI InChI=1S/C20H14F3NO4S/c21-20(22,23)28-15-8-6-12(7-9-15)14-10-16(29-11-14)18(25)24-17(19(26)27)13-4-2-1-3-5-13/h1-11,17H,(H,24,25)(H,26,27)/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Matrix metalloprotease-13				Bioorg Med Chem Lett 15: 3787-90 (2005) Article DOI: 10.1016/j.bmcl.2005.05.079 BindingDB Entry DOI: 10.7270/Q2736QFM
					More data for this Ligand-Target Pair