BDBM50170339 1-(1-Pentyl-1H-indol-3-yl)-2-o-tolyl-ethanone::1-(1-pentyl-1H-indol-3-yl)-2-o-tolylethanone::CHEMBL364820::JWH-251
SMILES: CCCCCn1cc(C(=O)Cc2ccccc2C)c2ccccc12
InChI Key: InChIKey=YBIPNGRKUAVSBG-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM50170339 (1-(1-Pentyl-1H-indol-3-yl)-2-o-tolyl-ethanone | 1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University Curated by ChEMBL | Assay Description Binding affinity to displace [3H]CP-55,940 from CB1 receptor of rat brain | Bioorg Med Chem Lett 15: 4110-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.008 BindingDB Entry DOI: 10.7270/Q2KD1XGV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM50170339 (1-(1-Pentyl-1H-indol-3-yl)-2-o-tolyl-ethanone | 1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 29.0 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do Rio de Janeiro Curated by ChEMBL | Assay Description Displacement of [3H]CP-55940 from CB1 receptor in rat brain by filtration assay | Eur J Med Chem 44: 2482-96 (2009) Article DOI: 10.1016/j.ejmech.2009.01.026 BindingDB Entry DOI: 10.7270/Q2K64K9J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50170339 (1-(1-Pentyl-1H-indol-3-yl)-2-o-tolyl-ethanone | 1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 146 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clemson University Curated by ChEMBL | Assay Description Binding affinity to displace [3H]CP-55,940 from cloned human CB2 receptor | Bioorg Med Chem Lett 15: 4110-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.008 BindingDB Entry DOI: 10.7270/Q2KD1XGV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50170339 (1-(1-Pentyl-1H-indol-3-yl)-2-o-tolyl-ethanone | 1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 146 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do Rio de Janeiro Curated by ChEMBL | Assay Description Displacement of [3H]CP-55940 from human cloned CB2 receptor by filtration assay | Eur J Med Chem 44: 2482-96 (2009) Article DOI: 10.1016/j.ejmech.2009.01.026 BindingDB Entry DOI: 10.7270/Q2K64K9J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM50170339 (1-(1-Pentyl-1H-indol-3-yl)-2-o-tolyl-ethanone | 1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 29 | n/a | n/a | n/a | n/a |
Clemson University Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding at CB1 receptor in presence of 10 uM WIN-55,212-2 | Bioorg Med Chem Lett 15: 4110-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.008 BindingDB Entry DOI: 10.7270/Q2KD1XGV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50170339 (1-(1-Pentyl-1H-indol-3-yl)-2-o-tolyl-ethanone | 1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 8.30 | n/a | n/a | n/a | n/a |
Clemson University Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding at CB2 receptor in presence of 3 uM CP-55,940 | Bioorg Med Chem Lett 15: 4110-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.008 BindingDB Entry DOI: 10.7270/Q2KD1XGV | |||||||||||
More data for this Ligand-Target Pair |