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SMILES: CN(Cc1ccccc1)C(=O)CN(Cc1ccc(OCC(O)=O)cc1)Cc1ccc(cc1)C(F)(F)P(O)(O)=O

InChI Key: InChIKey=BIPKVPVSZBSWAN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50171102   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50171102
PNG
(CHEMBL199133 | [4-({[(Benzyl-methyl-carbamoyl)-met...)
Show SMILES CN(Cc1ccccc1)C(=O)CN(Cc1ccc(OCC(O)=O)cc1)Cc1ccc(cc1)C(F)(F)P(O)(O)=O
Show InChI InChI=1S/C27H29F2N2O7P/c1-30(15-20-5-3-2-4-6-20)25(32)18-31(17-22-9-13-24(14-10-22)38-19-26(33)34)16-21-7-11-23(12-8-21)27(28,29)39(35,36)37/h2-14H,15-19H2,1H3,(H,33,34)(H2,35,36,37)
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MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.75E+4n/an/an/an/an/an/a



Affymax, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphate

Bioorg Med Chem Lett 15: 4336-41 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.061
BindingDB Entry DOI: 10.7270/Q2M61JSK
More data for this
Ligand-Target Pair