BDBM50171575 5-Chloro-N-[1-(4-chloro-benzyl)-piperidin-4-yl]-2-[(furan-2-ylmethyl)-amino]-nicotinamide::CHEMBL193489

SMILES: Clc1ccc(CN2CCC(CC2)NC(=O)c2cc(Cl)cnc2NCc2ccco2)cc1

InChI Key: InChIKey=CBNHBNWNTKQCFT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50171575   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50171575 (5-Chloro-N-[1-(4-chloro-benzyl)-piperidin-4-yl]-2-...) Show SMILES Clc1ccc(CN2CCC(CC2)NC(=O)c2cc(Cl)cnc2NCc2ccco2)cc1 Show InChI InChI=1S/C23H24Cl2N4O2/c24-17-5-3-16(4-6-17)15-29-9-7-19(8-10-29)28-23(30)21-12-18(25)13-26-22(21)27-14-20-2-1-11-31-20/h1-6,11-13,19H,7-10,14-15H2,(H,26,27)(H,28,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against MCH1R IMR32 cells in FLIPR-based assay				Bioorg Med Chem Lett 15: 4174-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.089 BindingDB Entry DOI: 10.7270/Q2N29WGN
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50171575 (5-Chloro-N-[1-(4-chloro-benzyl)-piperidin-4-yl]-2-...) Show SMILES Clc1ccc(CN2CCC(CC2)NC(=O)c2cc(Cl)cnc2NCc2ccco2)cc1 Show InChI InChI=1S/C23H24Cl2N4O2/c24-17-5-3-16(4-6-17)15-29-9-7-19(8-10-29)28-23(30)21-12-18(25)13-26-22(21)27-14-20-2-1-11-31-20/h1-6,11-13,19H,7-10,14-15H2,(H,26,27)(H,28,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity towards melanin-concentrating hormone receptor 1 in IMR32 cells				Bioorg Med Chem Lett 15: 4174-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.089 BindingDB Entry DOI: 10.7270/Q2N29WGN
					More data for this Ligand-Target Pair