BDBM50171599 CHEMBL371129::N-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-4-yl)-5-methoxy-2-[(tetrahydro-furan-3-ylmethyl)-amino]-benzamide

SMILES: COc1ccc(NCC2CCOC2)c(c1)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1

InChI Key: InChIKey=MZEFPTGQCBVZSL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50171599   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50171599 (CHEMBL371129 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...) Show SMILES COc1ccc(NCC2CCOC2)c(c1)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1 Show InChI InChI=1S/C26H33N3O5/c1-31-21-3-4-23(27-14-19-8-11-32-16-19)22(13-21)26(30)28-20-6-9-29(10-7-20)15-18-2-5-24-25(12-18)34-17-33-24/h2-5,12-13,19-20,27H,6-11,14-17H2,1H3,(H,28,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against MCH1R IMR32 cells in FLIPR-based assay				Bioorg Med Chem Lett 15: 4174-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.089 BindingDB Entry DOI: 10.7270/Q2N29WGN
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50171599 (CHEMBL371129 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...) Show SMILES COc1ccc(NCC2CCOC2)c(c1)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1 Show InChI InChI=1S/C26H33N3O5/c1-31-21-3-4-23(27-14-19-8-11-32-16-19)22(13-21)26(30)28-20-6-9-29(10-7-20)15-18-2-5-24-25(12-18)34-17-33-24/h2-5,12-13,19-20,27H,6-11,14-17H2,1H3,(H,28,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity towards melanin-concentrating hormone receptor 1 in IMR32 cells				Bioorg Med Chem Lett 15: 4174-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.089 BindingDB Entry DOI: 10.7270/Q2N29WGN
					More data for this Ligand-Target Pair