BDBM50172449 (E)-3-(4-Methoxy-phenyl)-N-(4-methyl-2-morpholin-4-yl-quinolin-6-yl)-acrylamide::CHEMBL194468

SMILES: COc1ccc(\C=C\C(=O)Nc2ccc3nc(cc(C)c3c2)N2CCOCC2)cc1

InChI Key: InChIKey=GZXQNWJYYPQVSJ-BJMVGYQFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50172449   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50172449 ((E)-3-(4-Methoxy-phenyl)-N-(4-methyl-2-morpholin-4...) Show SMILES COc1ccc(\C=C\C(=O)Nc2ccc3nc(cc(C)c3c2)N2CCOCC2)cc1 Show InChI InChI=1S/C24H25N3O3/c1-17-15-23(27-11-13-30-14-12-27)26-22-9-6-19(16-21(17)22)25-24(28)10-5-18-3-7-20(29-2)8-4-18/h3-10,15-16H,11-14H2,1-2H3,(H,25,28)/b10-5+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Displacement of 150p M [125I]-MCH from human MCH1R expressed in CHO-K1 cells				J Med Chem 48: 5684-97 (2005) Article DOI: 10.1021/jm050103y BindingDB Entry DOI: 10.7270/Q2H41QZ8
					More data for this Ligand-Target Pair