BDBM50172952 CHEMBL193588::{4-[6-Amino-4-(5-chloro-2-ethoxy-phenyl)-pyridin-2-ylamino]-phenyl}-methanol

SMILES: CCOc1ccc(Cl)cc1-c1cc(N)nc(Nc2ccc(CO)cc2)c1

InChI Key: InChIKey=BDOZQGIPSDJVJJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50172952   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
1-acylglycerol-3-phosphate O-acyltransferase beta (Homo sapiens (Human))	BDBM50172952 (CHEMBL193588 | {4-[6-Amino-4-(5-chloro-2-ethoxy-ph...) Show SMILES CCOc1ccc(Cl)cc1-c1cc(N)nc(Nc2ccc(CO)cc2)c1 Show InChI InChI=1S/C20H20ClN3O2/c1-2-26-18-8-5-15(21)11-17(18)14-9-19(22)24-20(10-14)23-16-6-3-13(12-25)4-7-16/h3-11,25H,2,12H2,1H3,(H3,22,23,24)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
Cell Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane				Bioorg Med Chem Lett 15: 4703-7 (2005) Article DOI: 10.1016/j.bmcl.2005.07.055 BindingDB Entry DOI: 10.7270/Q29G5MB2
					More data for this Ligand-Target Pair