BDBM50173040 4-[4-(2,4-Dimethyl-phenylamino)-phthalazin-1-yl]-benzamide::CHEMBL196705

SMILES: Cc1ccc(Nc2nnc(-c3ccc(cc3)C(N)=O)c3ccccc23)c(C)c1

InChI Key: InChIKey=LOFLDMZRIDDPSL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50173040   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50173040 (4-[4-(2,4-Dimethyl-phenylamino)-phthalazin-1-yl]-b...) Show SMILES Cc1ccc(Nc2nnc(-c3ccc(cc3)C(N)=O)c3ccccc23)c(C)c1 Show InChI InChI=1S/C23H20N4O/c1-14-7-12-20(15(2)13-14)25-23-19-6-4-3-5-18(19)21(26-27-23)16-8-10-17(11-9-16)22(24)28/h3-13H,1-2H3,(H2,24,28)(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide				Bioorg Med Chem Lett 15: 4696-8 (2005) Article DOI: 10.1016/j.bmcl.2005.07.064 BindingDB Entry DOI: 10.7270/Q25Q4VNS
					More data for this Ligand-Target Pair