BDBM50173603 CHEMBL3808622

SMILES: CC(C)(C)c1cc(NC(=O)n2ccc3cc(Oc4ncnc5CNCc45)ccc23)n[nH]1

InChI Key: InChIKey=UOZNOQSGMACPCZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50173603   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50173603 (CHEMBL3808622) Show SMILES CC(C)(C)c1cc(NC(=O)n2ccc3cc(Oc4ncnc5CNCc45)ccc23)n[nH]1 Show InChI InChI=1S/C22H23N7O2/c1-22(2,3)18-9-19(28-27-18)26-21(30)29-7-6-13-8-14(4-5-17(13)29)31-20-15-10-23-11-16(15)24-12-25-20/h4-9,12,23H,10-11H2,1-3H3,(H2,26,27,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse Baf3 cells				ACS Med Chem Lett 7: 363-7 (2016) BindingDB Entry DOI: 10.7270/Q24J0H11
					More data for this Ligand-Target Pair