BDBM50173608 CHEMBL371920::N-[4-(2-Ethyl-4-m-tolyl-thiazol-5-yl)-pyridin-2-yl]-acetamide

SMILES: CCc1nc(c(s1)-c1ccnc(NC(C)=O)c1)-c1cccc(C)c1

InChI Key: InChIKey=IZNYNBDTJRTLTA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50173608   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50173608 (CHEMBL371920 | N-[4-(2-Ethyl-4-m-tolyl-thiazol-5-y...) Show SMILES CCc1nc(c(s1)-c1ccnc(NC(C)=O)c1)-c1cccc(C)c1 Show InChI InChI=1S/C19H19N3OS/c1-4-17-22-18(14-7-5-6-12(2)10-14)19(24-17)15-8-9-20-16(11-15)21-13(3)23/h5-11H,4H2,1-3H3,(H,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory activity against mitogen-activated protein kinase p38 alpha				J Med Chem 48: 5966-79 (2005) Article DOI: 10.1021/jm050165o BindingDB Entry DOI: 10.7270/Q2G160DZ
					More data for this Ligand-Target Pair