BDBM50173649 4-[(E)-2-(4-Amino-phenyl)-vinyl]-phenol::CHEMBL194754::Stilbene derivative, 1
SMILES: Nc1ccc(\C=C\c2ccc(O)cc2)cc1
InChI Key: InChIKey=HGDVTCNLNRCTHW-OWOJBTEDSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Beta amyloid A4 protein (Homo sapiens (Human)) | BDBM50173649 (4-[(E)-2-(4-Amino-phenyl)-vinyl]-phenol | CHEMBL19...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 95 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant for I-125-IMPY binding to amyloid plaques in Alzheimers disease brain homogenates | J Med Chem 48: 5980-8 (2005) Article DOI: 10.1021/jm050166g BindingDB Entry DOI: 10.7270/Q2TB17PR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-glucosidase MAL12 (Saccharomyces cerevisiae) | BDBM50173649 (4-[(E)-2-(4-Amino-phenyl)-vinyl]-phenol | CHEMBL19...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University | Assay Description All enzymatic activities were determined by using the appropriate substrate (p-nitrophenyl-alpha-D-glucopyranoside, p-nitrophenyl-beta-D-gulcopyranos... | Chembiochem 11: 2125-31 (2010) Article DOI: 10.1002/cbic.201000376 BindingDB Entry DOI: 10.7270/Q2542M33 | |||||||||||
More data for this Ligand-Target Pair |