BDBM50173712 3-((1S,2S)-2-Dimethylaminomethyl-cyclopropyl)-1-ethyl-1H-indole-5-carbonitrile::CHEMBL199054
SMILES: CCn1cc([C@H]2C[C@@H]2CN(C)C)c2cc(ccc12)C#N
InChI Key: InChIKey=FBYZEHXPWUZCPM-KGLIPLIRSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50173712 (3-((1S,2S)-2-Dimethylaminomethyl-cyclopropyl)-1-et...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding inhibition towards human serotonin transporter | J Med Chem 48: 6023-34 (2005) Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN | |||||||||||
More data for this Ligand-Target Pair |