BDBM50173938 CHEMBL3808493
SMILES: CNC(=O)c1ccc2n([C@@H]3CCC[C@@H](C3)NC(=O)c3ccc(Br)n3C)c(nc2c1)-c1ccccn1
InChI Key: InChIKey=BHHKEFRQFWWDLQ-ZWKOTPCHSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Branched-chain-amino-acid aminotransferase, mitochondrial (Homo sapiens (Human)) | BDBM50173938 (CHEMBL3808493) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of human BCATm (28 to 392 residues) using L-Leucine and alpha-ketogluterate as substrate assessed as L-glutamate production after 10 mins ... | ACS Med Chem Lett 7: 379-84 (2016) BindingDB Entry DOI: 10.7270/Q2W097V6 | |||||||||||
More data for this Ligand-Target Pair |