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SMILES: COc1cc2NC(C)(\C=C\c3ccccc3)N(C)C(=O)c2cc1-c1cnco1

InChI Key: InChIKey=FOEGPJQZDBTZHI-MDZDMXLPSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174790   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Inosine-5'-monophosphate dehydrogenase 2


(Homo sapiens (Human))		BDBM50174790
PNG
(7-methoxy-2,3-dimethyl-6-(oxazol-5-yl)-2-styryl-2,...)
Show SMILES COc1cc2NC(C)(\C=C\c3ccccc3)N(C)C(=O)c2cc1-c1cnco1
Show InChI InChI=1S/C22H21N3O3/c1-22(10-9-15-7-5-4-6-8-15)24-18-12-19(27-3)17(20-13-23-14-28-20)11-16(18)21(26)25(22)2/h4-14,24H,1-3H3/b10-9+
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MMDB

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n/an/a 49n/an/an/an/an/an/a



UCB Celltech

Curated by ChEMBL


Assay Description
Inhibitory activity against IMPDH II

Bioorg Med Chem Lett 15: 5335-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.108
BindingDB Entry DOI: 10.7270/Q2CZ36P8
More data for this
Ligand-Target Pair