null
SMILES: Fc1ccc(NC(=O)N(CCCN2CCCC2)Cc2ccc(cc2)-c2cccc(c2)C#N)cc1C(F)(F)F
InChI Key: InChIKey=ORFTYWWDBBBBRZ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50174821 (1-(3'-cyano-biphenyl-4-ylmethyl)-3-(4-fluoro-3-tri...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Antagonist activity against human MCH1 receptor | Bioorg Med Chem Lett 15: 5234-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.043 BindingDB Entry DOI: 10.7270/Q24F1Q80 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 2 (Homo sapiens (Human)) | BDBM50174821 (1-(3'-cyano-biphenyl-4-ylmethyl)-3-(4-fluoro-3-tri...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Antagonist activity against human MCH2 receptor | Bioorg Med Chem Lett 15: 5234-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.043 BindingDB Entry DOI: 10.7270/Q24F1Q80 | |||||||||||
More data for this Ligand-Target Pair |