BDBM50174868 CHEMBL409589::X3-Apc-DPhe-Arg-Trp-Z9-NH2

SMILES: NC(N)=NCCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@]1(CC[C@@H](CC1)c1ccccc1)NC(=O)Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)Nc1ccccc1C(N)=O

InChI Key: InChIKey=GFASNSVXGRTMOT-DXRSDILLSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174868   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50174868 (CHEMBL409589 | X3-Apc-DPhe-Arg-Trp-Z9-NH2) Show SMILES NC(N)=NCCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@]1(CC[C@@H](CC1)c1ccccc1)NC(=O)Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)Nc1ccccc1C(N)=O |wU:7.7,25.29,11.19,22.36,wD:47.50,22.22,(15.73,-39.53,;14.39,-40.31,;13.06,-39.53,;14.39,-41.86,;13.06,-42.63,;13.06,-44.17,;11.72,-44.94,;11.72,-46.48,;10.38,-47.26,;9.04,-46.48,;9.04,-44.94,;7.71,-47.26,;7.71,-48.8,;9.04,-49.57,;9.03,-51.12,;10.37,-51.89,;11.71,-51.12,;11.7,-49.57,;10.37,-48.8,;6.38,-46.48,;5.03,-47.26,;5.03,-48.8,;3.7,-46.48,;5.03,-45.72,;5.04,-44.19,;3.71,-43.42,;2.38,-44.18,;2.37,-45.73,;3.72,-41.88,;5.06,-41.12,;5.06,-39.59,;3.73,-38.81,;2.4,-39.58,;2.4,-41.12,;2.36,-47.26,;1.02,-46.48,;1.02,-44.94,;-.31,-47.26,;-1.64,-46.49,;-1.64,-44.96,;-2.96,-44.19,;-4.3,-44.96,;-4.28,-46.5,;-2.95,-47.27,;13.06,-47.26,;13.06,-48.8,;14.39,-46.48,;15.73,-47.26,;15.73,-48.8,;17.07,-49.57,;18.41,-48.79,;19.51,-50.09,;18.75,-51.43,;19.23,-52.89,;18.19,-54.03,;16.68,-53.72,;16.21,-52.24,;17.24,-51.1,;17.07,-46.48,;17.07,-44.94,;18.41,-47.26,;19.74,-46.48,;20.81,-47.58,;22.3,-47.21,;22.71,-45.73,;21.63,-44.62,;20.15,-45.01,;19.07,-43.92,;19.48,-42.43,;17.58,-44.3,)| Show InChI InChI=1S/C54H60N10O6/c55-48(66)41-22-11-13-24-43(41)60-51(69)46(33-39-34-59-42-23-12-10-21-40(39)42)62-49(67)44(25-14-30-58-53(56)57)61-50(68)45(31-35-15-4-1-5-16-35)63-52(70)54(64-47(65)32-36-17-6-2-7-18-36)28-26-38(27-29-54)37-19-8-3-9-20-37/h1-13,15-24,34,38,44-46,59H,14,25-33H2,(H2,55,66)(H,60,69)(H,61,68)(H,62,67)(H,63,70)(H,64,65)(H4,56,57,58)/t38-,44-,45+,46-,54+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
Roche Research Center Curated by ChEMBL					Assay Description Agonist activity in HEK293 cells transfected with human MC4R by cAMP accumulation				Bioorg Med Chem Lett 15: 5504-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.083 BindingDB Entry DOI: 10.7270/Q2MC8ZK7
					More data for this Ligand-Target Pair