BDBM50174992 CHEMBL3809180

SMILES: Clc1ccc(Oc2cc(Cl)cc(CN3CCN(CC3)C(=O)Nc3cccnc3)c2)cc1

InChI Key: InChIKey=IDIWVJJNQDQXPV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174992   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50174992 (CHEMBL3809180) Show SMILES Clc1ccc(Oc2cc(Cl)cc(CN3CCN(CC3)C(=O)Nc3cccnc3)c2)cc1 Show InChI InChI=1S/C23H22Cl2N4O2/c24-18-3-5-21(6-4-18)31-22-13-17(12-19(25)14-22)16-28-8-10-29(11-9-28)23(30)27-20-2-1-7-26-15-20/h1-7,12-15H,8-11,16H2,(H,27,30)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson& Johnson, L.L.C. Curated by ChEMBL					Assay Description Apparent inhibition of recombinant rat FAAH expressed in SK-N-MC cells assessed as [3H]-anandamide hydrolysis after 1 hr by liquid scintillation anal...				Bioorg Med Chem Lett 26: 3109-14 (2016) BindingDB Entry DOI: 10.7270/Q25B04F3
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50174992 (CHEMBL3809180) Show SMILES Clc1ccc(Oc2cc(Cl)cc(CN3CCN(CC3)C(=O)Nc3cccnc3)c2)cc1 Show InChI InChI=1S/C23H22Cl2N4O2/c24-18-3-5-21(6-4-18)31-22-13-17(12-19(25)14-22)16-28-8-10-29(11-9-28)23(30)27-20-2-1-7-26-15-20/h1-7,12-15H,8-11,16H2,(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson& Johnson, L.L.C. Curated by ChEMBL					Assay Description Apparent inhibition of recombinant human FAAH expressed in SK-N-MC cells assessed as [3H]-anandamide hydrolysis after 1 hr by liquid scintillation an...				Bioorg Med Chem Lett 26: 3109-14 (2016) BindingDB Entry DOI: 10.7270/Q25B04F3
					More data for this Ligand-Target Pair