BDBM50175391 (R)-1-((R)-1-Biphenyl-3-ylmethyl-pyrrolidin-2-yl)-2-(1,1-dimethyl-2-naphthalen-2-yl-ethylamino)-ethanol::CHEMBL425394

SMILES: CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)[C@H]1CCCN1Cc1cccc(c1)-c1ccccc1

InChI Key: InChIKey=HAVCLXMWRUTARG-ROJLCIKYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175391   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50175391 ((R)-1-((R)-1-Biphenyl-3-ylmethyl-pyrrolidin-2-yl)-...) Show SMILES CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)[C@H]1CCCN1Cc1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C33H38N2O/c1-33(2,22-25-17-18-28-13-6-7-14-29(28)20-25)34-23-32(36)31-16-9-19-35(31)24-26-10-8-15-30(21-26)27-11-4-3-5-12-27/h3-8,10-15,17-18,20-21,31-32,34,36H,9,16,19,22-24H2,1-2H3/t31-,32-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPR				Bioorg Med Chem Lett 15: 5478-82 (2005) Article DOI: 10.1016/j.bmcl.2005.08.095 BindingDB Entry DOI: 10.7270/Q2WS8STX
					More data for this Ligand-Target Pair