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SMILES: COc1ccc(CCCN2CCN(C)CC2)cc1-c1[nH]nc2nc(Nc3ccc(F)cc3F)ncc12

InChI Key: InChIKey=ZBJHZMBCJCODSD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50176005   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Mus musculus (mouse))		BDBM50176005
PNG
(CHEMBL381457 | N-(2,4-difluorophenyl)-3-(2-methoxy...)
Show SMILES COc1ccc(CCCN2CCN(C)CC2)cc1-c1[nH]nc2nc(Nc3ccc(F)cc3F)ncc12
Show InChI InChI=1S/C26H29F2N7O/c1-34-10-12-35(13-11-34)9-3-4-17-5-8-23(36-2)19(14-17)24-20-16-29-26(31-25(20)33-32-24)30-22-7-6-18(27)15-21(22)28/h5-8,14-16H,3-4,9-13H2,1-2H3,(H2,29,30,31,32,33)
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Article
PubMed
n/an/a 14n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibitory activity against murine p38alpha MAPK

Bioorg Med Chem Lett 16: 262-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.10.015
BindingDB Entry DOI: 10.7270/Q2DJ5F6T
More data for this
Ligand-Target Pair