BDBM50176067 CHEMBL3809748

SMILES: Cl.COc1cccc(CCC2CCN(CCc3ccc(F)cc3)CC2)c1

InChI Key: InChIKey=DLCOTTJSGBFYAT-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50176067   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50176067 (CHEMBL3809748) Show SMILES Cl.COc1cccc(CCC2CCN(CCc3ccc(F)cc3)CC2)c1 Show InChI InChI=1S/C22H28FNO.ClH/c1-25-22-4-2-3-20(17-22)6-5-19-12-15-24(16-13-19)14-11-18-7-9-21(23)10-8-18;/h2-4,7-10,17,19H,5-6,11-16H2,1H3;1H	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition of [3H]DA uptake at VMAT2 in rat striata vesicles homogenate after 8 mins by liquid scintillation counting				Bioorg Med Chem Lett 26: 2997-3000 (2016) BindingDB Entry DOI: 10.7270/Q2MC91ZC
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50176067 (CHEMBL3809748) Show SMILES Cl.COc1cccc(CCC2CCN(CCc3ccc(F)cc3)CC2)c1 Show InChI InChI=1S/C22H28FNO.ClH/c1-25-22-4-2-3-20(17-22)6-5-19-12-15-24(16-13-19)14-11-18-7-9-21(23)10-8-18;/h2-4,7-10,17,19H,5-6,11-16H2,1H3;1H	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Displacement of [3H]DTBZ from VMAT2 in rat whole brain vesicles homogenate after 30 mins by liquid scintillation counting				Bioorg Med Chem Lett 26: 2997-3000 (2016) BindingDB Entry DOI: 10.7270/Q2MC91ZC
					More data for this Ligand-Target Pair