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BDBM50176073 3-{4-[Bis-(2-hydroxy-ethyl)-amino]-butyl}-6-(3-ethyl-4-methyl-phenylamino)-1H-pyrimidine-2,4-dione::CHEMBL196264

SMILES: CCc1cc(Nc2cc(=O)n(CCCCN(CCO)CCO)c(=O)[nH]2)ccc1C

InChI Key: InChIKey=BKEJFISZZNRSGE-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50176073   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA polymerase IIIC


(Bacillus subtilis)		BDBM50176073
PNG
(3-{4-[Bis-(2-hydroxy-ethyl)-amino]-butyl}-6-(3-eth...)
Show SMILES CCc1cc(Nc2cc(=O)n(CCCCN(CCO)CCO)c(=O)[nH]2)ccc1C
Show InChI InChI=1S/C21H32N4O4/c1-3-17-14-18(7-6-16(17)2)22-19-15-20(28)25(21(29)23-19)9-5-4-8-24(10-12-26)11-13-27/h6-7,14-15,22,26-27H,3-5,8-13H2,1-2H3,(H,23,29)
KEGG

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UniProtKB/TrEMBL

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Similars
Article
PubMed
 21n/an/an/an/an/an/an/an/a



GLSynthesis Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against Bacillus subtilis DNA polymerase IIIC using [3H]dTMP 250 pM (30 degree C for 10 min)

J Med Chem 48: 7063-74 (2005)


Article DOI: 10.1021/jm050517r
BindingDB Entry DOI: 10.7270/Q2W66MJN
More data for this
Ligand-Target Pair