BDBM50176630 2-(5-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)-2,3-dihydro-1H-inden-1-yl)propanoic acid::CHEMBL434945

SMILES: CC(C1CCc2cc(OCCc3nc(oc3C)-c3ccccc3)ccc12)C(O)=O

InChI Key: InChIKey=RHCUEKCLUOBRJM-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50176630   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50176630 (2-(5-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)-2,3-...) Show SMILES CC(C1CCc2cc(OCCc3nc(oc3C)-c3ccccc3)ccc12)C(O)=O Show InChI InChI=1S/C24H25NO4/c1-15(24(26)27)20-10-8-18-14-19(9-11-21(18)20)28-13-12-22-16(2)29-23(25-22)17-6-4-3-5-7-17/h3-7,9,11,14-15,20H,8,10,12-13H2,1-2H3,(H,26,27)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Activity against PPAR alpha in human by FRET assay				Bioorg Med Chem Lett 16: 297-301 (2005) Article DOI: 10.1016/j.bmcl.2005.10.008 BindingDB Entry DOI: 10.7270/Q28P6025
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50176630 (2-(5-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)-2,3-...) Show SMILES CC(C1CCc2cc(OCCc3nc(oc3C)-c3ccccc3)ccc12)C(O)=O Show InChI InChI=1S/C24H25NO4/c1-15(24(26)27)20-10-8-18-14-19(9-11-21(18)20)28-13-12-22-16(2)29-23(25-22)17-6-4-3-5-7-17/h3-7,9,11,14-15,20H,8,10,12-13H2,1-2H3,(H,26,27)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	220	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Agonist activity at PPARalpha by FRET assay				Bioorg Med Chem Lett 17: 4369-73 (2007) Article DOI: 10.1016/j.bmcl.2007.03.057 BindingDB Entry DOI: 10.7270/Q2GX4B8H
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50176630 (2-(5-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)-2,3-...) Show SMILES CC(C1CCc2cc(OCCc3nc(oc3C)-c3ccccc3)ccc12)C(O)=O Show InChI InChI=1S/C24H25NO4/c1-15(24(26)27)20-10-8-18-14-19(9-11-21(18)20)28-13-12-22-16(2)29-23(25-22)17-6-4-3-5-7-17/h3-7,9,11,14-15,20H,8,10,12-13H2,1-2H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Agonist activity at GST-tagged human PPARdelta by FRET assay				Bioorg Med Chem Lett 17: 4369-73 (2007) Article DOI: 10.1016/j.bmcl.2007.03.057 BindingDB Entry DOI: 10.7270/Q2GX4B8H
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50176630 (2-(5-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)-2,3-...) Show SMILES CC(C1CCc2cc(OCCc3nc(oc3C)-c3ccccc3)ccc12)C(O)=O Show InChI InChI=1S/C24H25NO4/c1-15(24(26)27)20-10-8-18-14-19(9-11-21(18)20)28-13-12-22-16(2)29-23(25-22)17-6-4-3-5-7-17/h3-7,9,11,14-15,20H,8,10,12-13H2,1-2H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	104	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Activity against PPAR gamma in human by FRET assay				Bioorg Med Chem Lett 16: 297-301 (2005) Article DOI: 10.1016/j.bmcl.2005.10.008 BindingDB Entry DOI: 10.7270/Q28P6025
					More data for this Ligand-Target Pair