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BDBM50176939 (2S)-1-((S)-2-aminobutanoyl)-4-benzyl-N-butylpyrrolidine-2-carboxamide::CHEMBL224451

SMILES: CCCCNC(=O)[C@@H]1CC(Cc2ccccc2)CN1C(=O)[C@@H](N)CC

InChI Key: InChIKey=CADQCYDPKBWFDJ-FQECFTEESA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50176939   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tripeptidyl aminopeptidase


(Rattus norvegicus)
BDBM50176939
PNG
((2S)-1-((S)-2-aminobutanoyl)-4-benzyl-N-butylpyrro...)
Show SMILES CCCCNC(=O)[C@@H]1CC(Cc2ccccc2)CN1C(=O)[C@@H](N)CC |r|
Show InChI InChI=1S/C20H31N3O2/c1-3-5-11-22-19(24)18-13-16(12-15-9-7-6-8-10-15)14-23(18)20(25)17(21)4-2/h6-10,16-18H,3-5,11-14,21H2,1-2H3,(H,22,24)/t16?,17-,18-/m0/s1
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PC cid
PC sid
UniChem
Article
PubMed
140n/an/an/an/an/an/an/an/a



University College London

Curated by ChEMBL


Assay Description
Inhibition of TPPII in rat cererbral membrane


J Med Chem 48: 7333-42 (2005)


Article DOI: 10.1021/jm0500830
BindingDB Entry DOI: 10.7270/Q2KK9CMS
More data for this
Ligand-Target Pair