BDBM50177209 6-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-3,5-difluoro-pyridin-2-yloxy]-N-(2,6-dimethyl-benzyl)-isophthalamic acid trifluoro-acetic acid::CHEMBL201901

SMILES: CC(C)N(C(C)C)c1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)C(=O)NCc2c(C)cccc2C)c1F

InChI Key: InChIKey=OIBTZCAULCDYDI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50177209   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50177209 (6-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) Show SMILES CC(C)N(C(C)C)c1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)C(=O)NCc2c(C)cccc2C)c1F Show InChI InChI=1S/C35H37F2N5O5/c1-18(2)42(19(3)4)30-28(36)33(46-24-12-8-11-22(15-24)31(38)39)41-34(29(30)37)47-27-14-13-23(16-25(27)35(44)45)32(43)40-17-26-20(5)9-7-10-21(26)6/h7-16,18-19H,17H2,1-6H3,(H3,38,39)(H,40,43)(H,44,45)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of FIIa				Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW
					More data for this Ligand-Target Pair
Coagulation factor III/Factor VIIa (fVIIa) (Homo sapiens (Human))	BDBM50177209 (6-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) Show SMILES CC(C)N(C(C)C)c1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)C(=O)NCc2c(C)cccc2C)c1F Show InChI InChI=1S/C35H37F2N5O5/c1-18(2)42(19(3)4)30-28(36)33(46-24-12-8-11-22(15-24)31(38)39)41-34(29(30)37)47-27-14-13-23(16-25(27)35(44)45)32(43)40-17-26-20(5)9-7-10-21(26)6/h7-16,18-19H,17H2,1-6H3,(H3,38,39)(H,40,43)(H,44,45)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant FVIIa/TF complex				Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW
					More data for this Ligand-Target Pair