BDBM50177213 4-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-3,5-difluoro-pyridin-2-yloxy]-3'-methyl-biphenyl-3-carboxylic acid trifluoro-acetic acid::CHEMBL382572

SMILES: CC(C)N(C(C)C)c1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)-c2cccc(C)c2)c1F

InChI Key: InChIKey=AHSBJTPSJRAMDU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50177213   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50177213 (4-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) Show SMILES CC(C)N(C(C)C)c1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)-c2cccc(C)c2)c1F Show InChI InChI=1S/C32H32F2N4O4/c1-17(2)38(18(3)4)28-26(33)30(41-23-11-7-10-22(15-23)29(35)36)37-31(27(28)34)42-25-13-12-21(16-24(25)32(39)40)20-9-6-8-19(5)14-20/h6-18H,1-5H3,(H3,35,36)(H,39,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of FIIa				Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW
					More data for this Ligand-Target Pair
Coagulation factor III/Factor VIIa (fVIIa) (Homo sapiens (Human))	BDBM50177213 (4-[6-(3-carbamimidoyl-phenoxy)-4-diisopropylamino-...) Show SMILES CC(C)N(C(C)C)c1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2ccc(cc2C(O)=O)-c2cccc(C)c2)c1F Show InChI InChI=1S/C32H32F2N4O4/c1-17(2)38(18(3)4)28-26(33)30(41-23-11-7-10-22(15-23)29(35)36)37-31(27(28)34)42-25-13-12-21(16-24(25)32(39)40)20-9-6-8-19(5)14-20/h6-18H,1-5H3,(H3,35,36)(H,39,40)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant FVIIa/TF complex				Bioorg Med Chem Lett 16: 1060-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.076 BindingDB Entry DOI: 10.7270/Q2Q81DWW
					More data for this Ligand-Target Pair